RE2O / ECM Skin Rejuvenation

"hADM-Based ECM Skin Booster Designed to Support the Skin’s Structural Environment"

A personalized skin rejuvenation program that delivers extracellular matrix (ECM) components derived from human acellular dermal matrix (hADM) into the dermis to support skin structure and improve the appearance of elasticity, texture, enlarged pores, and overall skin quality.

RE2O / ECM Skin Rejuvenation thumbnail

What Is Elravie RE2O?

Elravie RE2O is an extracellular matrix (ECM)-based skin booster derived from human acellular dermal matrix (hADM). It is designed to support the structural environment of the skin by delivering processed dermal matrix components into the treatment area.

Why Is the Extracellular Matrix Important?

Skin aging involves not only a reduction in collagen but also changes in the extracellular matrix that surrounds and supports skin cells. The ECM provides a structural framework containing components associated with skin integrity, elasticity, hydration, and tissue organization.

How Does Elravie RE2O Work?

Elravie RE2O contains processed ECM components derived from hADM. These components may include structural proteins and glycosaminoglycans associated with the dermal matrix. When administered into the skin, the treatment is intended to support the local tissue environment and natural remodeling processes.

What Improvements May Be Expected?

By supporting the skin’s structural environment, Elravie RE2O may help improve the appearance of reduced elasticity, uneven texture, enlarged pores, and decreased skin density. Results develop gradually and vary according to individual skin condition and treatment response.

How Is Elravie RE2O Different from PN Skin Boosters?

PN-based treatments such as REJURAN® are designed to support the skin’s regenerative environment using polynucleotides. Elravie RE2O uses hADM-derived ECM components and focuses on supporting the extracellular framework associated with dermal structure.

Can It Be Combined with Other Delivery Methods?

Depending on skin condition and treatment goals, Elravie RE2O may be administered through direct injection or combined with a controlled delivery system such as the POTENZA Pumping Tip or HYCOOX. The appropriate treatment method is determined after an individual assessment.

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Recommended Interval
Recommended at approximately 4-week intervals
Recommended Sessions
A series of approximately 3 sessions is generally recommended
Recovery Time
Bruising, swelling, and injection-related changes may require approximately 1–2 weeks to fully settle

Benefits

01Supports the skin’s structural environment
02May improve the appearance of reduced skin elasticity
03May help refine uneven or rough skin texture
04May improve the appearance of enlarged pores
05May support overall skin density and quality
06Promotes healthier-looking skin over time

Recommended For

01Supports the skin’s structural environment
02May improve the appearance of reduced skin elasticity
03May help refine uneven or rough skin texture
04May improve the appearance of enlarged pores
05May support overall skin density and quality
06Promotes healthier-looking skin over time

Treatment Process

STEP 01Personalized Consultation
STEP 02Skin Analysis
STEP 03Customized Elravie RE2O Treatment
STEP 04Finishing Care and Post-Treatment Instructions

FAQ

01

What benefits can I expect from Elravie RE2O?

Elravie RE2O is designed to support the skin’s extracellular matrix environment and may improve the appearance of elasticity, texture, enlarged pores, skin density, and overall skin quality.

02

How many treatments are recommended?

The recommended number varies according to individual skin condition and treatment goals. A series of approximately three sessions at four-week intervals is commonly recommended.

03

How is Elravie RE2O different from REJURAN®?

REJURAN® is a PN-based skin booster designed to support the skin’s regenerative environment. Elravie RE2O contains hADM-derived extracellular matrix components and is intended to support the structural framework of the dermis.

04

Can I return to normal activities immediately after treatment?

Most patients can continue normal daily activities, but temporary injection bumps, redness, swelling, bruising, or tenderness may be visible. Depending on the injection method and individual response, these changes may take approximately one to two weeks to fully resolve.

05

Can Elravie RE2O be combined with POTENZA?

Depending on skin condition and treatment goals, Elravie RE2O may be combined with a delivery method such as the POTENZA Pumping Tip. The suitability and treatment settings should be determined after consultation.

06

When will I notice results?

The timing varies among individuals. Early changes in hydration or skin texture may be noticed first, while improvements associated with tissue remodeling generally develop gradually over the following weeks.

Precautions

Temporary bruising, swelling, redness, tenderness, injection bumps, or small needle marks may occur and may take approximately 1–2 weeks to fully resolve.
Raised injection areas generally improve within several hours to several days, depending on the injection method and individual skin response.
Avoid pressing, rubbing, or vigorously massaging the treated area for approximately one week unless specifically instructed by your medical provider.
Avoid alcohol, smoking, saunas, steam rooms, hot baths, and strenuous exercise for approximately 2–3 days after treatment.
Temporary dryness or tightness may occur, so maintain adequate hydration and apply broad-spectrum sunscreen regularly.
Contact your medical provider if bruising or swelling persists longer than expected, or if worsening pain, heat, discharge, fever, significant inflammation, or other unusual symptoms develop.
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