REJURAN® / Skin Rejuvenation

"PN Skin Booster Designed to Support the Skin’s Natural Regenerative Environment"

A personalized skin rejuvenation program that delivers polynucleotide (PN) into the dermis to support skin recovery and improve the appearance of skin texture, elasticity, fine lines, hydration, and overall skin quality.

REJURAN® / Skin Rejuvenation thumbnail

What Is REJURAN®?

REJURAN® is a polynucleotide-based injectable treatment designed to improve the overall skin environment. Salmon-derived polynucleotide (PN) is delivered into the dermis to support the skin’s natural repair and regenerative processes.

How Does REJURAN® Work?

PN delivered into the dermis supports an environment associated with fibroblast activity and collagen remodeling. This may help improve the appearance of skin texture, elasticity, fine lines, hydration, and overall skin quality over time.

What Is REJURAN® Healer?

REJURAN® Healer is designed for full-face skin rejuvenation. It is commonly selected for patients concerned about uneven skin texture, reduced elasticity, fine lines, and an overall decline in skin quality.

What Is REJURAN® i?

REJURAN® i is formulated for delicate areas with thin skin, particularly the eye area. It may help improve the appearance of fine lines, crepey texture, and reduced firmness around the eyes.

What Is REJURAN® HB Plus?

REJURAN® HB Plus combines PN with hyaluronic acid and lidocaine. Hyaluronic acid supports hydration, while lidocaine is included to reduce injection-related discomfort compared with the original formulation.

What Is REJURAN® s?

REJURAN® s has a higher-viscosity formulation designed for scars and localized depressed areas. It may be considered for selected atrophic acne scars or focal skin depressions after an individual assessment.

Which Delivery Methods Are Available?

REJURAN® may be administered through manual intradermal injections or with an injector such as HYCOOX. The POTENZA Pumping Tip may also be considered to support even distribution through its microneedle pumping mechanism. The appropriate method is selected according to skin condition, treatment area, and individual goals.

Why Is Personalized Treatment Planning Important?

The most appropriate REJURAN® formulation, injection depth, dosage, and delivery method vary depending on skin thickness, sensitivity, treatment area, and primary skin concerns. A personalized plan helps provide balanced and natural-looking skin rejuvenation.

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Recommended Interval
Recommended at approximately 3–4-week intervals
Recommended Sessions
A series of approximately 3 sessions is generally recommended
Recovery Time
Normal daily activities can usually be resumed on the same day

Benefits

01Supports the skin’s natural regenerative environment
02May improve the appearance of uneven skin texture
03May support skin firmness and elasticity
04May soften the appearance of fine lines
05Supports skin hydration and overall barrier condition
06May help maintain healthier-looking skin

Recommended For

01Those with sensitive or compromised-looking skin
02Those whose skin requires repeated recovery and rejuvenation
03Those concerned about uneven skin texture or enlarged-looking pores
04Those concerned about reduced elasticity and fine lines
05Those seeking a personalized polynucleotide skin rejuvenation program

Treatment Process

STEP 01Personalized Consultation
STEP 02Topical Anesthetic Application
STEP 03Customized REJURAN® Treatment
STEP 04Finishing Care and Post-Treatment Instructions

FAQ

01

What benefits can I expect from REJURAN®?

REJURAN® supports the skin’s regenerative environment and may improve the appearance of skin texture, elasticity, fine lines, hydration, and overall skin quality.

02

How many REJURAN® treatments are recommended?

The recommended number varies according to individual skin condition. A series of approximately three or more sessions at intervals of three to four weeks is commonly recommended.

03

Is REJURAN® treatment painful?

Some discomfort may occur because the product is injected into the dermis. REJURAN® HB Plus, which contains lidocaine, or additional pain-management and injector options may be considered to reduce treatment-related discomfort.

04

Can REJURAN® be administered with the POTENZA Pumping Tip or HYCOOX?

Yes. Depending on skin condition and treatment goals, HYCOOX or the POTENZA Pumping Tip may be used to support controlled and even product delivery. The appropriate delivery method is determined after consultation.

05

How long do the injection bumps last?

Small raised bumps may temporarily appear where the product has been placed in the dermis. Depending on the injection method, dosage, and individual skin response, they generally subside within several hours to approximately one to three days.

06

Can REJURAN® be performed after laser treatment?

REJURAN® may be incorporated into a post-laser skin recovery program in selected cases. The appropriate timing and treatment method depend on the type of laser procedure and the current condition of the skin.

Precautions

Temporary raised injection bumps, swelling, redness, bruising, tenderness, or small needle marks may occur and generally improve within several days.
Do not press, rub, or massage raised injection sites unless specifically instructed by your medical provider.
Avoid alcohol, smoking, saunas, steam rooms, hot baths, and strenuous exercise for approximately 2–3 days after treatment.
Follow your medical provider’s instructions regarding cleansing and makeup, and avoid excessive rubbing or irritation of the treated area.
Maintain adequate skin hydration and apply broad-spectrum sunscreen regularly after treatment.
Contact your medical provider if severe or worsening swelling, pain, heat, discharge, signs of infection, or other unusual symptoms occur.
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